The Khorda Avesta and Yašt Codex E1. Facsimile Edition.Wiesbaden, Harrassowitz, 2008, 607 p. (IRANICA, 16)

Functional mapping of the human papillomavirus type 16 E1 cistron.

Replication of the double-stranded, circular human papillomavirus (HPV) genomes requires the viral DNA replicase E1. Here, we report an initial characterization of the E1 cistron of HPV type 16 (HPV-16), the most common oncogenic mucosal HPV type found in cervical and some head and neck cancers. The first step in HPV DNA replication is an initial burst of plasmid viral DNA amplification. Comple...

The Ophthalmic Prescriber's Codex

Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1.

UNLABELLED NF-κB is a family of transcription factors that regulate gene expression involved in many processes, such as the inflammatory response and cancer progression. Little is known about associations of NF-κB with the human papillomavirus (HPV) life cycle. We have developed a tissue culture system to conditionally induce E1-dependent replication of the human papillomavirus 16 (HPV16) genom...

Phytochemical and Chemotaxonomic Investigation of Stelleropsis iranica

Stelleropsis genus belongs to Thymelaeaceae and has two species in Iran of which S. iranica Pobed. subsp. Iranica Bonge (aerial parts) were collected from the North-East of Iran and extracted with AcOEt and MeOH, consequently. The main phenolic compounds were isolated by different chromatography methods and the structures identified by spectroscopic methods (1H-NMR, 13C-NMR, HMBC, HMQC, H-H COS...

The Archimedes Codex

We learned, of course, something of the curious story of the oldest (by 400 years) surviving manuscript of some of Arch imedes ’ works, collected in a Byzantine codex that contained the end of Equilibrium of Planes , great parts of The Sphere and the Cylinder and Measurement of the Circle, a sizable portion of On Floating Bodies, one folio of The Stomachion, and a large portion of The Method. T...